SGO_1655 protein (Streptococcus gordonii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SGO_1655

CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471. (446 aa)

Predicted Functional Partners:

guaA

0.655

SGO_1656

0.561

fruA

0.505

SGO_1657

0.485

topA

0.480

ybeY

0.472

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_1655	SGO_1656	SGO_1655	SGO_1656	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	Phosphoenolpyruvate carboxykinase.	0.561
SGO_1655	SGO_1657	SGO_1655	SGO_1657	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	Identified by match to protein family HMM PF01594.	0.485
SGO_1655	fruA	SGO_1655	SGO_1113	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.	0.505
SGO_1655	guaA	SGO_1655	SGO_1120	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.655
SGO_1655	topA	SGO_1655	SGO_1197	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.480
SGO_1655	ybeY	SGO_1655	SGO_0711	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.472
SGO_1656	SGO_1655	SGO_1656	SGO_1655	Phosphoenolpyruvate carboxykinase.	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.561
SGO_1656	SGO_1657	SGO_1656	SGO_1657	Phosphoenolpyruvate carboxykinase.	Identified by match to protein family HMM PF01594.	0.528
SGO_1657	SGO_1655	SGO_1657	SGO_1655	Identified by match to protein family HMM PF01594.	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.485
SGO_1657	SGO_1656	SGO_1657	SGO_1656	Identified by match to protein family HMM PF01594.	Phosphoenolpyruvate carboxykinase.	0.528
SGO_1657	ybeY	SGO_1657	SGO_0711	Identified by match to protein family HMM PF01594.	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.583
fruA	SGO_1655	SGO_1113	SGO_1655	PTS system, fructose specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.505
guaA	SGO_1655	SGO_1120	SGO_1655	GMP synthase; Catalyzes the synthesis of GMP from XMP.	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.655
guaA	topA	SGO_1120	SGO_1197	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.591
guaA	ybeY	SGO_1120	SGO_0711	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.447
topA	SGO_1655	SGO_1197	SGO_1655	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.480
topA	guaA	SGO_1197	SGO_1120	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.591
topA	ybeY	SGO_1197	SGO_0711	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.747
ybeY	SGO_1655	SGO_0711	SGO_1655	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	CBS domain protein/possible hemolysin; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.	0.472
ybeY	SGO_1657	SGO_0711	SGO_1657	Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	Identified by match to protein family HMM PF01594.	0.583

page 1 of 2

Server load: medium (50%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About