STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hppAOligopeptide-binding lipoprotein; May be involved in the expression of cell surface properties important for colonization of the human oral cavity. It may also be involved in uptake processes; Belongs to the bacterial solute-binding protein 5 family. (663 aa)    
Predicted Functional Partners:
amiD
Oligopeptide transport system permease protein; Identified by match to protein family HMM PF00528.
 
 
 0.996
amiE
Oligopeptide transport ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily.
 
 
 0.993
hppB
Oligopeptide transport system permease; Identified by match to protein family HMM PF00528.
 
 
 0.993
amiF
Oligopeptide transport ATP-binding protein amiF; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; Belongs to the ABC transporter superfamily.
 
 
 0.991
hppG
Oligopeptide-binding lipoprotein; Identified by match to protein family HMM PF00496.
 
  
0.940
hppH
Oligopeptide-binding lipoprotein; Identified by match to protein family HMM PF00496.
  
  
0.904
SGO_1716
Oligopeptide binding protein; Identified by match to protein family HMM PF00496.
  
  
 
0.902
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
      
 0.584
SGO_0524
HD domain protein; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277.
   
  
 0.576
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
      
 0.576
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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