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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1769Protein of unknown function (DUF1237) superfamily; Identified by match to protein family HMM PF06824. (429 aa)    
Predicted Functional Partners:
SGO_1768
Glycosyl hydrolase, family 38; Identified by match to protein family HMM PF01074; match to protein family HMM PF07748.
 
    0.938
SGO_1770
Glycosyl hydrolase; Identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180.
    0.923
SGO_1763
ABC transporter, substrate-binding protein SP0092; Identified by match to protein family HMM PF01547.
 
     0.838
SGO_1762
Protein of unknown function, DUF624 family; Identified by match to protein family HMM PF04854.
 
     0.818
SGO_1765
ABC transporter sugar binding protein; Identified by match to protein family HMM PF00528.
 
    0.813
SGO_1766
Glycosyl hydrolase family 20, catalytic domain family; Identified by match to protein family HMM PF00728.
 
     0.801
SGO_1764
ABC transporter, permease protein SP0091; Identified by match to protein family HMM PF00528.
 
     0.760
SGO_1760
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
 
    0.696
SGO_1486
Beta-galactosidase; Identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
 
     0.695
SGO_1761
Histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580.
 
     0.670
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.