close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scaRScaR Manganese-dependent regulator of scaCBA; Identified by similarity to GB:AAF25184.1; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023. (215 aa)    
Predicted Functional Partners:
troB
Manganese ABC transporter, ATP-binding protein SP1648; Identified by match to protein family HMM PF00005.
  
  
 0.717
SGO_1802
Metal ABC transporter substrate-binding lipoprotein precursor; Identified by match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.717
scaA
ABC transporter membrane-spanning permease - manganese transport; Identified by match to protein family HMM PF00950.
 
  
 0.706
metN
ABC transporter, ATP-binding protein SP0151; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
    
   0.612
SGO_1817
Transcription regulator, MarR-family; Identified by similarity to GB:AAF25185.1; match to protein family HMM PF01047.
  
  
 0.571
SGO_0703
Ferric transport regulator protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
  
 0.561
SGO_1818
Conserved hypothetical protein; Identified by match to protein family HMM PF01878; Belongs to the UPF0310 family.
       0.546
SGO_1815
Conserved hypothetical protein.
     
 0.522
nadR
Transcription regulator; Identified by match to protein family HMM TIGR00125.
   
    0.461
adcA
Metal-binding (Mn) permease precursor, lipoprotein; Identified by match to protein family HMM PF01297; match to protein family HMM PF09223; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.455
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.