node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_0695 | SGO_1852 | SGO_0695 | SGO_1852 | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | 0.551 |
SGO_0695 | metG | SGO_0695 | SGO_1530 | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.535 |
SGO_0695 | sun | SGO_0695 | SGO_0598 | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.517 |
SGO_0695 | topA | SGO_0695 | SGO_1197 | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.574 |
SGO_0695 | uppS | SGO_0695 | SGO_1854 | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.971 |
SGO_1852 | SGO_0695 | SGO_1852 | SGO_0695 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.551 |
SGO_1852 | cdsA | SGO_1852 | SGO_1853 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | 0.778 |
SGO_1852 | csn1 | SGO_1852 | SGO_1381 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...] | 0.572 |
SGO_1852 | degP | SGO_1852 | SGO_2150 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | 0.547 |
SGO_1852 | metG | SGO_1852 | SGO_1530 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.569 |
SGO_1852 | proS | SGO_1852 | SGO_1851 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.771 |
SGO_1852 | sun | SGO_1852 | SGO_0598 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.617 |
SGO_1852 | topA | SGO_1852 | SGO_1197 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.644 |
SGO_1852 | uppS | SGO_1852 | SGO_1854 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.826 |
SGO_1852 | zmpC | SGO_1852 | SGO_0942 | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | Zinc metalloproteinase C; Identified by match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07554; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01168. | 0.635 |
cdsA | SGO_1852 | SGO_1853 | SGO_1852 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | 0.778 |
cdsA | proS | SGO_1853 | SGO_1851 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.512 |
cdsA | topA | SGO_1853 | SGO_1197 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.479 |
cdsA | uppS | SGO_1853 | SGO_1854 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.978 |
csn1 | SGO_1852 | SGO_1381 | SGO_1852 | CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...] | Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054. | 0.572 |