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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_1883Membrane protein, putative. (273 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
       0.620
SGO_1743
Identified by match to protein family HMM PF06182.
  
     0.525
SGO_1742
Protein of unknown function (DUF990) superfamily; Identified by match to protein family HMM PF06182.
  
     0.510
sgc
Serine protease challisin; Identified by match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF04650; match to protein family HMM PF06280; match to protein family HMM PF07554; match to protein family HMM TIGR01168.
  
     0.461
SGO_0317
LPXTG cell wall surface protein, serine protease, subtilase family; Identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF04650; match to protein family HMM PF06280; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
  
     0.454
SGO_0316
LPXTG cell wall surface protein, serine protease, subtilase family; Identified by match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF04650; match to protein family HMM PF06280; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
  
     0.439
SGO_1744
ABC transporter, ATP-binding protein SP0636; Identified by match to protein family HMM PF00005.
  
     0.419
zmpB
Zinc metalloproteinase B; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
  
     0.415
SGO_2067
Conserved membrane protein, putative multidrug efflux associated; Identified by match to protein family HMM PF06182.
  
     0.403
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
       0.401
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.