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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadRTranscription regulator; Identified by match to protein family HMM TIGR00125. (352 aa)    
Predicted Functional Partners:
SGO_1996
Nicotinamide mononucleotide transporter PnuC subfamily, putative; Identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528.
 
   
 0.974
cobB
NAD-dependent deacetylase (Regulatory protein SIR2-like protein); NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
  
 0.909
SGO_1917
Conserved hypothetical protein.
   
    0.908
SGO_0480
Conserved hypothetical protein; Identified by match to protein family HMM PF06983.
   
    0.744
SGO_0582
Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.702
SGO_1995
Identified by match to protein family HMM PF00293.
     
 0.675
SGO_0042
Transcription regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
   
    0.667
SGO_1121
Transcription regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
   
    0.667
SGO_1654
Trehalose operon transcription repressor; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404.
   
    0.667
SGO_1194
Phosphoribosylanthranilate isomerase, putative.
  
     0.655
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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