Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbp2aPenicillin-binding protein 2A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074. (740 aa)    
Predicted Functional Partners:
pbp2b
Penicillin-binding protein 2B; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
 
 0.996
pbp2X
Penicillin-binding protein 2X; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793.
 
 
0.988
pbp3
Penicillin-binding protein 3; Identified by match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
   
 
 0.967
pbp1b
Penicillin-binding protein 1B; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912.
  
  
0.944
pbp1a
Penicillin-binding protein 1A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
  
  
0.943
gpsB
Methylase; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.907
mreB
Cell shape determining protein; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
  
 
 
 0.905
SGO_0843
Carboxypeptidase; Identified by match to protein family HMM PF02557.
     
 0.902
SGO_0393
D-alanyl-D-alanine carboxypeptidase; Identified by match to protein family HMM PF02557.
     
 0.901
SGO_0759
Cell division protein FtsW; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
  
 
 
 0.887
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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