STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tarINucleotidyl transferase, putative; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (240 aa)    
Predicted Functional Partners:
SGO_2016
Nucleotide sugar dehydratase, putative; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993.
 
   
 0.889
licD
licD3 protein; Identified by match to protein family HMM PF04991.
 
   
 0.866
SGO_2018
Extrracellular polysaccharide polymerase putative.
       0.800
SGO_2015
Possible polysaccharide transport protein.
  
    0.798
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
  
 0.787
SGO_1912
Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.687
SGO_2023
Galactosyltransferase; Identified by match to protein family HMM PF02397.
  
  
 0.629
SGO_2022
UDP-glucose 4-epimerase BH3715; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.
     
 0.619
SGO_2020
Glycosyltransferase; Identified by match to protein family HMM PF00535.
  
  
 0.615
SGO_2021
Extracellular polysaccharide glycosyltransferase; Identified by match to protein family HMM PF00535.
  
  
 0.615
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.