SGO_2075 protein (Streptococcus gordonii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SGO_2075

Plasmid replication protein; Identified by match to protein family HMM PF01719. (204 aa)

Predicted Functional Partners:

dnaA

0.833

carA

0.833

guaA

0.759

pyrE

0.747

pyrC

0.744

pyrK

0.731

pyrB

0.728

pyrF

0.728

SGO_0035

0.674

argG

0.657

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_0035	SGO_2075	SGO_0035	SGO_2075	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Plasmid replication protein; Identified by match to protein family HMM PF01719.	0.674
SGO_0035	argG	SGO_0035	SGO_0175	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.	0.530
SGO_0035	carA	SGO_0035	SGO_1103	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	0.911
SGO_0035	dnaA	SGO_0035	SGO_0001	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.899
SGO_0035	guaA	SGO_0035	SGO_1120	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.975
SGO_0035	pyrB	SGO_0035	SGO_1109	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.715
SGO_0035	pyrC	SGO_0035	SGO_1248	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.663
SGO_0035	pyrE	SGO_0035	SGO_1253	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.763
SGO_0035	pyrF	SGO_0035	SGO_1254	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.736
SGO_0035	pyrK	SGO_0035	SGO_1256	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).	0.425
SGO_2075	SGO_0035	SGO_2075	SGO_0035	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.	0.674
SGO_2075	argG	SGO_2075	SGO_0175	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.	0.657
SGO_2075	carA	SGO_2075	SGO_1103	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.	0.833
SGO_2075	dnaA	SGO_2075	SGO_0001	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.833
SGO_2075	guaA	SGO_2075	SGO_1120	Plasmid replication protein; Identified by match to protein family HMM PF01719.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.759
SGO_2075	pyrB	SGO_2075	SGO_1109	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.728
SGO_2075	pyrC	SGO_2075	SGO_1248	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.744
SGO_2075	pyrE	SGO_2075	SGO_1253	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.747
SGO_2075	pyrF	SGO_2075	SGO_1254	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.728
SGO_2075	pyrK	SGO_2075	SGO_1256	Plasmid replication protein; Identified by match to protein family HMM PF01719.	Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).	0.731

page 1 of 5

Server load: low (32%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About