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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_2094General stress protein GSP-781; Identified by match to protein family HMM PF05257; match to protein family HMM PF08481. (549 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.705
SGO_1699
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
  
   
 0.626
nrdD
Ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF01228; match to protein family HMM PF03477; match to protein family HMM TIGR02487.
   
  
 0.598
SGO_0385
exo-beta-D-fructosidase; Identified by match to protein family HMM PF00251; match to protein family HMM PF00746; match to protein family HMM PF02368; match to protein family HMM PF07501; match to protein family HMM PF07554; match to protein family HMM PF08244; match to protein family HMM TIGR01167.
  
  
 0.586
ftsX
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
  
  
 0.582
SGO_1750
ABC-type multidrug/protein/lipid transport system, ATPase component; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
      
 0.573
SGO_2093
Hypothetical protein; Identified by Glimmer2; putative.
       0.572
ftsE
Cell-division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
  
 0.506
purD
Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02655; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM PF08442; match to protein family HMM TIGR00877; Belongs to the GARS family.
       0.472
SGO_2091
Conserved hypothetical protein.
 
     0.450
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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