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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comBTransport protein ComB; Identified by match to protein family HMM TIGR01000. (452 aa)    
Predicted Functional Partners:
comA
ATP-binding Transport protein ComA; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193.
 
 
 0.992
SGO_2005
LPXTG cell wall surface protein; Identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167.
  
 
 0.917
comE
Competence response regulator ComE; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
     
 0.659
comC
Competence factor-related protein ComC; Identified by match to protein family HMM PF03047; match to protein family HMM TIGR01847.
      
 0.624
comD
Histidine protein kinase ComD; Identified by match to protein family HMM PF02518.
  
  
 0.608
SGO_1750
ABC-type multidrug/protein/lipid transport system, ATPase component; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
      
 0.606
relA
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
  
 0.594
comX
ComX.
      
 0.580
SGO_1575
Competence protein CoiA; Identified by match to protein family HMM PF06054.
      
 0.570
SGO_0752
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF02687.
  
  
 0.528
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.