Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
comDHistidine protein kinase ComD; Identified by match to protein family HMM PF02518. (453 aa)    
Predicted Functional Partners:
comE
Competence response regulator ComE; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
 
 
 0.998
comC
Competence factor-related protein ComC; Identified by match to protein family HMM PF03047; match to protein family HMM TIGR01847.
     
 0.918
SGO_1130
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
    
 0.883
SGO_0374
Response regulator of the LytR/AlgR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
 
  
 0.833
SGO_1417
Response regulator protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
   
 
 0.674
comYA
Competence protein comYA; Identified by match to protein family HMM PF00437.
      
 0.605
rlmH
Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
  
    0.602
SGO_1761
Histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580.
  
   
 0.600
comX
ComX.
      
 0.595
SGO_1732
Histidine kinase; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730.
   
 
 0.592
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.