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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degPSerine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. (397 aa)    
Predicted Functional Partners:
ciaR
Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
  
 0.923
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.823
fabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.715
spo0J
Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
     
 0.661
ftsE
Cell-division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
  
 0.643
sthA
Bacteriocin; Identified by match to protein family HMM TIGR01847.
      
 0.625
zmpB
Zinc metalloproteinase B; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
      
 0.612
SGO_1180
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 0.601
adk
Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.597
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  
 0.591
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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