node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_1460 | polI | SGO_1460 | SGO_0145 | DNA translocase ftsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.676 |
SGO_1460 | spo0J | SGO_1460 | SGO_2151 | DNA translocase ftsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.764 |
SGO_1460 | topA | SGO_1460 | SGO_1197 | DNA translocase ftsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.557 |
ciaR | degP | SGO_1072 | SGO_2150 | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | 0.923 |
ciaR | infB | SGO_1072 | SGO_0546 | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.611 |
ciaR | rbfA | SGO_1072 | SGO_0547 | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.622 |
ciaR | rimP | SGO_1072 | SGO_0542 | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.592 |
ciaR | spo0J | SGO_1072 | SGO_2151 | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.622 |
degP | ciaR | SGO_2150 | SGO_1072 | Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.923 |
degP | polI | SGO_2150 | SGO_0145 | Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.527 |
degP | spo0J | SGO_2150 | SGO_2151 | Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595. | Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.661 |
ftsZ | polI | SGO_0675 | SGO_0145 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.492 |
ftsZ | spo0J | SGO_0675 | SGO_2151 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.609 |
ftsZ | topA | SGO_0675 | SGO_1197 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.494 |
gidB | polI | SGO_0491 | SGO_0145 | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.630 |
gidB | spo0J | SGO_0491 | SGO_2151 | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Chromosome segregation protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.674 |
infB | ciaR | SGO_0546 | SGO_1072 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Transcriptional regulatory protein CiaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.611 |
infB | polI | SGO_0546 | SGO_0145 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.676 |
infB | rbfA | SGO_0546 | SGO_0547 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.947 |
infB | rimP | SGO_0546 | SGO_0542 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.933 |