STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGIG_11577Dihydrolipoyllysine-residue succinyltransferase. (151 aa)    
Predicted Functional Partners:
FGIG_06036
Dihydrolipoamide dehydrogenase.
  
 0.998
FGIG_04989
2-oxoglutarate dehydrogenase mitochondrial.
  
 0.998
FGIG_05835
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.989
FGIG_00973
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.979
FGIG_10515
2-oxoisovalerate dehydrogenase subunit beta.
  
 0.977
FGIG_02962
Putative pyridine nucleotide-disulfide oxidoreductase.
  
 0.975
FGIG_04349
Citrate synthase; Belongs to the citrate synthase family.
  
 0.969
FGIG_09770
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.954
FGIG_07370
ATP synthetase.
  
 0.941
FGIG_01751
2-oxoglutarate dehydrogenase E1 component.
  
 0.936
Your Current Organism:
Fasciola gigantica
NCBI taxonomy Id: 46835
Other names: F. gigantica
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.