STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGIG_03748Chromodomain-helicase-DNA-binding protein 1. (1702 aa)    
Predicted Functional Partners:
FGIG_09470
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.936
FGIG_08231
FACT complex subunit.
    
 
 0.852
FGIG_01209
DNA-directed RNA polymerase II subunit C.
   
 0.844
FGIG_01984
Transcription elongation factor SPT5.
   
 
 0.783
FGIG_04339
Catenin (Cadherin-associated protein) beta 1.
    
 0.779
FGIG_04846
RNA polymerase associated protein RTF1.
   
 
 0.777
FGIG_02417
Histone H2A; Belongs to the histone H2A family.
    
 0.772
FGIG_11269
Dna directed rna polymerases i ii and iii.
    
 0.770
FGIG_02292
Fanconi anemia group M protein.
    
 0.770
FGIG_00910
RuvB-like helicase; Belongs to the RuvB family.
    
 0.768
Your Current Organism:
Fasciola gigantica
NCBI taxonomy Id: 46835
Other names: F. gigantica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.