STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGIG_07497FCH domain only protein 2. (449 aa)    
Predicted Functional Partners:
FGIG_11175
Intersectin-1.
   
 0.994
FGIG_08779
Uncharacterized protein.
   
 0.994
FGIG_04670
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
    
 0.932
FGIG_04615
Epidermal growth factor receptor substrate 15.
    
 0.929
FGIG_03599
AP-2 complex subunit mu-A; Belongs to the adaptor complexes medium subunit family.
   
 0.922
FGIG_02390
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.872
FGIG_03372
NECAP endocytosis-associated 2.
    
 0.866
FGIG_11174
Intersectin-1.
    
 0.864
FGIG_06955
AP complex subunit beta.
    
 0.854
FGIG_03191
AP complex subunit beta.
    
 0.854
Your Current Organism:
Fasciola gigantica
NCBI taxonomy Id: 46835
Other names: F. gigantica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.