STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JP75_16595Heme transporter; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (221 aa)    
Predicted Functional Partners:
ccmA
Hypothetical protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
ccmC
Heme transporter HemC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmE
Cytochrome C biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.946
JP75_16610
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.900
JP75_21470
Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.873
JP75_21465
Hypothetical protein; Possible subunit of a heme lyase.
 
   
 0.845
JP75_21480
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.738
JP75_16585
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
       0.575
JP75_19280
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.499
JP75_19210
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.414
Your Current Organism:
Devosia riboflavina
NCBI taxonomy Id: 46914
Other names: ATCC 9526, CIP 59.10, D. riboflavina, DSM 7230, IFO 13584, JCM 21244, LMG 2277, LMG:2277, NBRC 13584, NRRL B-2463, NRRL B-784, Pseudomonas riboflavina, strain Foster strain 4R3337
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