STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JP75_22635Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.904
JP75_22615
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.827
JP75_22620
Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.818
JP75_22640
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.812
JP75_22630
ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
    0.805
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.755
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.729
JP75_22610
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.711
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
     0.702
cpsB
Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.700
Your Current Organism:
Devosia riboflavina
NCBI taxonomy Id: 46914
Other names: ATCC 9526, CIP 59.10, D. riboflavina, DSM 7230, IFO 13584, JCM 21244, LMG 2277, LMG:2277, NBRC 13584, NRRL B-2463, NRRL B-784, Pseudomonas riboflavina, strain Foster strain 4R3337
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