Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tbis_0010KEGG: scl:sce7051 putative periplasmic substrate- binding protein. (280 aa)    
Predicted Functional Partners:
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
  
 0.812
Tbis_3128
PFAM: Uracil-DNA glycosylase superfamily; KEGG: ade:Adeh_3631 uracil-DNA glycosylase superfamily protein.
      0.666
Tbis_1233
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rce:RC1_0315 iron(III) dicitrate transport ATP-binding protein FecE.
 
 
 0.634
Tbis_1232
PFAM: transport system permease protein; KEGG: bha:BH1586 ferric ion ABC transpoter (permease); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.608
Tbis_1621
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dac:Daci_3149 ABC transporter related.
  
 
 0.586
Tbis_3496
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dal:Dalk_4058 ABC transporter related.
  
 
 0.586
Tbis_1623
PFAM: transport system permease protein; KEGG: atc:AGR_pAT_449 ferric enterobactin transport protein FepD; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.580
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
      0.569
Tbis_3497
PFAM: transport system permease protein; KEGG: ppd:Ppro_1257 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.561
Tbis_1812
PFAM: protein of unknown function DUF1023; KEGG: scl:sce3217 serine/threonine-protein kinase.
  
     0.447
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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