STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_0160KEGG: ade:Adeh_4279 UDP-N-acetylglucosamine 2- epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (375 aa)    
Predicted Functional Partners:
Tbis_0162
TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sus:Acid_4597 UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 0.999
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.924
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
 0.908
murA-2
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
 0.908
Tbis_0161
PFAM: glycosyl transferase group 1; KEGG: dar:Daro_2409 glycosyl transferase, group 1.
 
  
 0.907
Tbis_0891
PFAM: glycosyl transferase family 4; KEGG: bat:BAS5050 glycosyl transferase, group 4 family protein.
  
 0.822
Tbis_0163
PFAM: glycosyl transferase group 1; KEGG: bha:BH3662 glycosyltransferase (biosynthesis of lipopolisaccharide O antigen).
 
  
 0.791
Tbis_0713
Nucleotide sugar dehydrogenase; KEGG: acr:Acry_1348 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
 
  
 0.767
Tbis_1926
Membrane protein involved in the export of O- antigen and teichoic acid-like protein; KEGG: rle:pRL110396 putative transmembrane protein.
  
  
 0.764
Tbis_0726
PFAM: glycosyl transferase group 1; KEGG: bha:BH3662 glycosyltransferase (biosynthesis of lipopolisaccharide O antigen).
 
  
 0.667
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.