STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_0212KEGG: acp:A2cp1_0593 filamentation induced by cAMP protein Fic. (258 aa)    
Predicted Functional Partners:
Tbis_0495
Hypothetical protein.
  
     0.771
Tbis_3327
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_0422 acyl-CoA dehydrogenase.
  
     0.685
Tbis_1346
PFAM: GCN5-related N-acetyltransferase; KEGG: bce:BC2347 acetyltransferase.
  
     0.572
Tbis_0455
Hypothetical protein; KEGG: methyl-accepting chemotaxis sensory transducer with cache sensor.
  
     0.567
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.564
Tbis_0251
TIGRFAM: DNA binding domain protein, excisionase family; KEGG: bsu:BSU33370 hypothetical protein.
 
     0.521
Tbis_3407
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afw:Anae109_0009 hypothetical protein.
  
     0.520
Tbis_0461
Hypothetical protein.
  
     0.514
Tbis_0197
PFAM: Anion-transporting ATPase; KEGG: mxa:MXAN_5818 anion-transporting ATPase.
  
     0.484
Tbis_0210
PFAM: protein of unknown function DUF1469; KEGG: jan:Jann_2210 hypothetical protein.
 
     0.483
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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