STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_0534KEGG: aba:Acid345_0045 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase. (398 aa)    
Predicted Functional Partners:
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KEGG: afw:Anae109_0100 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
  
  
 
0.928
Tbis_1432
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
  
 
0.923
Tbis_0687
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.918
Tbis_1286
PFAM: PfkB domain protein; KEGG: dds:Ddes_0200 PfkB domain protein.
    
 0.912
Tbis_2587
Ribosylpyrimidine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: spe:Spro_4396 purine nucleosidase.
 
 
 0.911
Tbis_0452
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: scl:sce7039 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family.
    
 0.909
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.483
Tbis_0535
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ppd:Ppro_2189 aminotransferase, class I and II.
     
 0.456
Tbis_0533
PFAM: Methyltransferase type 12; Methyltransferase type 11; KEGG: mxa:MXAN_1023 putative pristinamycin I synthase 3.
  
    0.419
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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