STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (345 aa)    
Predicted Functional Partners:
Tbis_0614
PFAM: peptidase M22 glycoprotease; KEGG: pla:Plav_3613 peptidase M22 glycoprotease.
 0.999
Tbis_0611
PFAM: protein of unknown function UPF0079; KEGG: gbm:Gbem_1263 protein of unknown function UPF0079.
 
 0.998
Tbis_0615
TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: glo:Glov_2306 ribosomal-protein-alanine acetyltransferase.
  
 0.989
Tbis_2685
KEGG: rce:RC1_1749 hypothetical protein.
  
 0.977
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
  
 0.770
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.735
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.698
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.679
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
  
 0.676
Tbis_0890
TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: bca:BCE_5452 SUA5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
  
 
 0.666
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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