STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_0969PFAM: nitrogen regulatory protein P-II; KEGG: gbm:Gbem_3078 nitrogen regulatory protein P- II. (112 aa)    
Predicted Functional Partners:
Tbis_0968
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: sfu:Sfum_0727 ammonium transporter.
 
 0.999
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.924
Tbis_1458
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ade:Adeh_0817 glutamate synthase (NADH) large subunit.
 
  
 0.896
Tbis_1603
PFAM: ADP-ribosylation/Crystallin J1; KEGG: esa:ESA_00407 hypothetical protein.
   
 
 0.876
Tbis_1262
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: dal:Dalk_5100 glutamine synthetase, type I.
 
  
 0.843
Tbis_1133
KEGG: pap:PSPA7_4308 hypothetical protein.
    
 
 0.745
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
 
 
 0.745
Tbis_1698
KEGG: afw:Anae109_3949 heat domain-containing protein.
    
 
 0.745
Tbis_2017
KEGG: ank:AnaeK_3630 protein of unknown function DUF124.
    
 
 0.745
Tbis_2020
KEGG: bpm:BURPS1710b_1933 hypothetical protein.
    
 
 0.745
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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