STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_1027Tyrosine 3-monooxygenase; PFAM: aromatic amino acid hydroxylase; KEGG: hypothetical protein. (297 aa)    
Predicted Functional Partners:
Tbis_2684
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mxa:MXAN_6773 putative pterin-4-alpha- carbinolamine dehydratase.
  
 0.985
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ade:Adeh_1779 prephenate dehydratase.
     
 0.908
pat
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
     
 0.908
Tbis_0535
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ppd:Ppro_2189 aminotransferase, class I and II.
   
 
 0.908
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: bur:Bcep18194_C7445 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.908
Tbis_2568
PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: csa:Csal_1034 aminotransferase.
   
 
 0.908
Tbis_1107
PFAM: homogentisate 12-dioxygenase; Cupin 2 conserved barrel domain protein; KEGG: bcy:Bcer98_0230 homogentisate 12-dioxygenase.
 
  
 0.868
Tbis_1717
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: scl:sce5042 hypothetical protein.
     
  0.800
Tbis_3108
KEGG: bcy:Bcer98_0228 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.767
Tbis_1026
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: spl:Spea_0737 DNA-binding transcriptional regulator AsnC.
 
   
 0.608
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
Server load: low (20%) [HD]