STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)    
Predicted Functional Partners:
Tbis_1220
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
Tbis_1619
PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 putative acetyl-coenzyme A synthetase.
   
 
 0.974
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.970
Tbis_1865
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: bxe:Bxe_A1651 isocitrate lyase.
   
  
 0.945
Tbis_1575
PFAM: AMP-dependent synthetase and ligase; KEGG: tgr:Tgr7_1511 propionate--CoA ligase.
   
 
 0.926
Tbis_0364
PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce5007 putative aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
 
 
 0.917
Tbis_2533
PFAM: Aldehyde Dehydrogenase; KEGG: pca:Pcar_1701 aldehyde dehydrogenase, NAD- linked; Belongs to the aldehyde dehydrogenase family.
 
 
 0.917
Tbis_1585
PFAM: CoA-binding domain protein; KEGG: mgm:Mmc1_1098 CoA-binding domain protein.
    
 0.913
Tbis_2778
PFAM: acylphosphatase; KEGG: ecg:E2348C_0954 predicted acylphosphatase.
     
 0.912
Tbis_3504
Phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: noc:Noc_2717 putative phosphoketolase.
  
 0.906
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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