STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_1277Hypothetical protein. (72 aa)    
Predicted Functional Partners:
cobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
       0.622
Tbis_1276
PFAM: cobalbumin biosynthesis protein; KEGG: bxe:Bxe_A3493 adenosylcobinamide kinase.
       0.622
Tbis_1570
PFAM: Na+/solute symporter; KEGG: bac:BamMC406_2256 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
     0.563
Tbis_3000
KEGG: ade:Adeh_2859 hypothetical protein.
  
     0.531
Tbis_3537
Hypothetical protein.
  
     0.524
Tbis_1311
Hypothetical protein; KEGG: pak2b; p21 (CDKN1A)-activated kinase 2b; K04410 p21-activated kinase 2.
  
     0.523
Tbis_2480
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein.
  
     0.515
Tbis_2462
Conserved hypothetical protein; KEGG: glo:Glov_0470 radical SAM domain protein.
  
     0.469
fbiD
Protein of unknown function DUF121; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
  
     0.416
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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