STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_1830Hypothetical protein; KEGG: ZIC5; Zic family member 5 (odd-paired homolog, Drosophila); K09226 zinc finger protein ZIC 5. (212 aa)    
Predicted Functional Partners:
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
       0.558
prcA
20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
       0.479
prcB
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
       0.443
Tbis_1828
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: vsa:VSAL_I0305 FKBP-type peptidyl-prolyl cis- trans isomerase FkpA precursor.
       0.423
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.