close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_2016TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bsu:BSU32290 hypothetical protein. (333 aa)    
Predicted Functional Partners:
Tbis_2020
KEGG: bpm:BURPS1710b_1933 hypothetical protein.
  
 
 0.958
Tbis_1325
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
 
 0.914
Tbis_2017
KEGG: ank:AnaeK_3630 protein of unknown function DUF124.
   
 
 0.831
Tbis_2018
PFAM: conserved hypothetical protein; KEGG: afw:Anae109_1414 hypothetical protein.
       0.653
Tbis_2011
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
    
 0.618
Tbis_2050
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: gme:Gmet_0939 recombination factor protein RarA.
 
      0.585
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.582
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: glo:Glov_2147 cytidylate kinase.
  
    0.465
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
   0.445
Tbis_0723
PFAM: 3-dehydroquinate synthase; iron-containing alcohol dehydrogenase; KEGG: scl:sce5394 glycerol-1-phosphate dehydrogenase (NAD(P)(+)).
 
  
 0.438
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.