STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Tbis_2129TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: bcr:BCAH187_A1777 sodium/solute symporter family protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (537 aa)    
Predicted Functional Partners:
Tbis_2130
PFAM: protein of unknown function DUF485; KEGG: sus:Acid_0924 hypothetical protein.
 
  
 0.990
Tbis_2128
PFAM: regulatory protein TetR; KEGG: reh:H16_A0214 transcriptional regulator, TetR/AcrR-family.
       0.487
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.469
Tbis_1619
PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 putative acetyl-coenzyme A synthetase.
  
  
 0.457
Tbis_1575
PFAM: AMP-dependent synthetase and ligase; KEGG: tgr:Tgr7_1511 propionate--CoA ligase.
  
  
 0.430
Tbis_0788
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: cti:RALTA_A2344 acetoacetyl-coenzyme A synthetase (acetoacetate--CoA ligase 1) (acyl-activating enzyme 1).
  
  
 0.415
Tbis_2268
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: sfu:Sfum_1404 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
  
 0.405
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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