STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_2385PFAM: PfkB domain protein; KEGG: nar:Saro_0151 PfkB. (297 aa)    
Predicted Functional Partners:
Tbis_3076
PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein.
  
  
 0.633
hisA
Bifunctional HisA/TrpF protein; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: bifunctional HisA/TrpF protein; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein.
  
  
 0.576
Tbis_3075
PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sus:Acid_1483 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family.
  
  
 0.555
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 
 
 0.489
Tbis_2386
PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_00228 histone acetyltransferase HPA2- like acetyltransferase.
  
    0.438
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.426
Tbis_2400
Hypothetical protein.
  
     0.418
Tbis_1957
KEGG: scl:sce1864 hypothetical protein.
  
     0.414
Tbis_3079
Myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sit:TM1040_3346 xylose isomerase-like TIM barrel.
  
  
 0.413
Tbis_1458
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ade:Adeh_0817 glutamate synthase (NADH) large subunit.
    
 
 0.403
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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