STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_3264PFAM: band 7 protein; SMART: band 7 protein; KEGG: mxa:MXAN_3984 SPFH/band 7 domain protein. (359 aa)    
Predicted Functional Partners:
Tbis_3263
PFAM: protein of unknown function DUF107; KEGG: sfu:Sfum_2309 protein of unknown function DUF107.
 
  
 0.966
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.957
Tbis_0924
PFAM: protein of unknown function DUF179; KEGG: tgr:Tgr7_2910 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family.
   
    0.725
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.682
Tbis_1069
PFAM: peptidase M16 domain protein; KEGG: dal:Dalk_4744 peptidase M16 domain protein; Belongs to the peptidase M16 family.
  
 0.607
Tbis_3487
KEGG: sml:Smlt1262 hypothetical protein.
  
  
 0.604
Tbis_0058
PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein.
   
 0.589
Tbis_0518
PFAM: Rhomboid family protein; KEGG: lpp:lpp0886 hypothetical protein.
   
 0.589
Tbis_1043
PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1267 hypothetical protein.
  
    0.570
Tbis_3070
Hypothetical protein.
   
    0.562
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.