STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACU94698.1PFAM: Serine dehydratase alpha chain; ACT domain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, single chain form. (541 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.967
ACU94790.1
Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase.
     
 0.908
ACU93899.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain.
   
 
  0.814
ACU94699.1
Predicted membrane protein; PFAM: Protein of unknown function (DUF1113).
       0.761
Your Current Organism:
Cryptobacterium curtum
NCBI taxonomy Id: 469378
Other names: C. curtum DSM 15641, Cryptobacterium curtum 12-3, Cryptobacterium curtum ATCC 700683, Cryptobacterium curtum DSM 15641, Cryptobacterium curtum str. DSM 15641, Cryptobacterium curtum strain DSM 15641
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