STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (511 aa)    
Predicted Functional Partners:
ADQ67259.1
PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
 
 
 0.956
glpK-2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
  
 
0.900
ADQ67252.1
Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase.
 
 
 0.820
ADQ66034.1
Hypothetical protein.
     
 0.801
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 0.799
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 0.799
ADQ66504.1
Predicted metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family.
   
 0.790
ADQ67758.1
Proteasome Rpn11 subunit JAMM motif protein; PFAM: Mov34/MPN/PAD-1 family.
   
 0.790
psmA
20S proteasome subunit (alpha or beta); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.707
psmB
Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.707
Your Current Organism:
Halogeometricum borinquense
NCBI taxonomy Id: 469382
Other names: H. borinquense DSM 11551, Halogeometricum borinquense ATCC 700274, Halogeometricum borinquense DSM 11551, Halogeometricum borinquense JCM 10706, Halogeometricum borinquense PR 3, Halogeometricum borinquense str. DSM 11551, Halogeometricum borinquense strain DSM 11551
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