Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (200 aa)    
Predicted Functional Partners:
ADQ66819.1
Isopentenyl phosphate kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
    
 0.977
ADQ66782.1
Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.943
ADQ68410.1
Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.940
ADQ67386.1
PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase.
 
 
 0.907
ADQ66502.1
PFAM: Sigma-70, region 4; AsnC family.
       0.905
ADQ66658.1
Lycopene elongase; PFAM: UbiA prenyltransferase family.
 
 
 0.829
ADQ66449.1
PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal.
 
  
 0.825
ADQ66660.1
PFAM: Squalene/phytoene synthase.
 
  
 0.803
ADQ66504.1
Predicted metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family.
  
   0.797
ADQ66595.1
PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family.
  
  
 0.758
Your Current Organism:
Halogeometricum borinquense
NCBI taxonomy Id: 469382
Other names: H. borinquense DSM 11551, Halogeometricum borinquense ATCC 700274, Halogeometricum borinquense DSM 11551, Halogeometricum borinquense JCM 10706, Halogeometricum borinquense PR 3, Halogeometricum borinquense str. DSM 11551, Halogeometricum borinquense strain DSM 11551
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