STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (291 aa)    
Predicted Functional Partners:
Cwoe_0773
TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: ade:Adeh_0139 glycine oxidase ThiO.
 
 0.999
Cwoe_0774
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: pfs:PFLU5774 putative thiamine biosynthesis- related protein.
 
 
 0.999
Cwoe_1844
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: scl:sce3858 molybdopterin biosynthesis protein MoeB.
  
 0.998
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.993
Cwoe_3672
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; hydroxyethylthiazole kinase; KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase.
 
  
 0.967
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.951
Cwoe_1845
PFAM: thiamineS protein; KEGG: mxa:MXAN_4067 ThiS family protein.
   
 
 0.861
Cwoe_3192
TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: scl:sce5755 hypothetical protein.
   
 
 0.861
Cwoe_4090
KEGG: eba:p2A350 FO synthase; TIGRFAM: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; 7,8-didemethyl-8-hydroxy-5- deazariboflavin synthase, CofG subunit; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.812
Cwoe_4147
KEGG: eba:p2A350 FO synthase; TIGRFAM: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; 7,8-didemethyl-8-hydroxy-5- deazariboflavin synthase, CofG subunit; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.812
Your Current Organism:
Conexibacter woesei DSM 14684
NCBI taxonomy Id: 469383
Other names: C. woesei DSM 14684, Conexibacter woesei str. DSM 14684, Conexibacter woesei strain DSM 14684
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