STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (300 aa)    
Predicted Functional Partners:
Cwoe_4716
TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'- phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; KEGG: afw:Anae109_0939 DNA ligase D.
 
  
 0.962
Cwoe_5554
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: sme:SM_b20008 ATP-dependent DNA ligase.
 
  
 0.923
Cwoe_2717
PFAM: DNA primase small subunit; KEGG: afw:Anae109_0939 DNA ligase D.
 
  
 0.887
Cwoe_3833
PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit.
 
  
 0.887
Cwoe_3638
TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; PFAM: acylphosphatase; KEGG: bpy:Bphyt_1858 DNA ligase D.
  
     0.769
Cwoe_3430
KEGG: reh:H16_A1489 DNA topoisomerase IB.
 
    0.657
Cwoe_1813
TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 3 domain protein; sigma- 70 region 4 domain protein; KEGG: gem:GM21_2391 RNA polymerase, sigma 70 subunit, RpoD subfamily.
       0.594
Cwoe_1815
KEGG: xcb:XC_4140 hypothetical protein.
       0.472
Cwoe_1811
KEGG: rpa:RPA0935 hypothetical protein; Belongs to the UPF0255 family.
  
    0.457
Cwoe_5620
KEGG: sat:SYN_01806 putative cytoplasmic protein.
  
     0.444
Your Current Organism:
Conexibacter woesei DSM 14684
NCBI taxonomy Id: 469383
Other names: C. woesei DSM 14684, Conexibacter woesei str. DSM 14684, Conexibacter woesei strain DSM 14684
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