node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cwoe_1386 | Cwoe_1689 | Cwoe_1386 | Cwoe_1689 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.914 |
Cwoe_1386 | Cwoe_4457 | Cwoe_1386 | Cwoe_4457 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.914 |
Cwoe_1386 | hisA | Cwoe_1386 | Cwoe_3528 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | KEGG: dde:Dde_1465 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.887 |
Cwoe_1386 | hisB | Cwoe_1386 | Cwoe_3530 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: rpa:RPA0309 imidazoleglycerol-phosphate dehydratase. | 0.996 |
Cwoe_1386 | hisC | Cwoe_1386 | Cwoe_3739 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: cti:RALTA_A0774 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.919 |
Cwoe_1386 | hisD-2 | Cwoe_1386 | Cwoe_3531 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.919 |
Cwoe_1386 | hisF | Cwoe_1386 | Cwoe_3527 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.888 |
Cwoe_1386 | hisG | Cwoe_1386 | Cwoe_3532 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.890 |
Cwoe_1386 | hisH | Cwoe_1386 | Cwoe_3529 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.912 |
Cwoe_1386 | hisI | Cwoe_1386 | Cwoe_2852 | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: scl:sce0397 hypothetical protein; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
Cwoe_1689 | Cwoe_1386 | Cwoe_1689 | Cwoe_1386 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | 0.914 |
Cwoe_1689 | Cwoe_4457 | Cwoe_1689 | Cwoe_4457 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.927 |
Cwoe_1689 | hisB | Cwoe_1689 | Cwoe_3530 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: rpa:RPA0309 imidazoleglycerol-phosphate dehydratase. | 0.406 |
Cwoe_1689 | hisC | Cwoe_1689 | Cwoe_3739 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: cti:RALTA_A0774 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.927 |
Cwoe_1689 | hisD-2 | Cwoe_1689 | Cwoe_3531 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.924 |
Cwoe_1689 | hisI | Cwoe_1689 | Cwoe_2852 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: scl:sce0397 hypothetical protein; In the N-terminal section; belongs to the PRA-CH family. | 0.714 |
Cwoe_4457 | Cwoe_1386 | Cwoe_4457 | Cwoe_1386 | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | PFAM: aminotransferase class I and II; KEGG: noc:Noc_0175 histidinol-phosphate aminotransferase. | 0.914 |
Cwoe_4457 | Cwoe_1689 | Cwoe_4457 | Cwoe_1689 | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: nam:NAMH_1464 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.927 |
Cwoe_4457 | hisB | Cwoe_4457 | Cwoe_3530 | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: rpa:RPA0309 imidazoleglycerol-phosphate dehydratase. | 0.406 |
Cwoe_4457 | hisC | Cwoe_4457 | Cwoe_3739 | PFAM: PHP domain protein; KEGG: wsu:WS0471 putative histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: cti:RALTA_A0774 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.914 |