STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cwoe_4926PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: vei:Veis_4212 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (615 aa)    
Predicted Functional Partners:
Cwoe_4925
PFAM: cyclase family protein; KEGG: vap:Vapar_0647 cyclase family protein.
 
     0.890
Cwoe_3579
TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3022 acetolactate synthase, small subunit.
 
 0.888
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.763
ilvD-2
KEGG: mes:Meso_1688 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.702
Cwoe_2147
PFAM: cyclase family protein; KEGG: oan:Oant_4027 cyclase family protein.
 
     0.650
Cwoe_4447
PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: aav:Aave_3759 dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.626
ilvD
KEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.597
Cwoe_0206
KEGG: mca:MCA1838 alpha-acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase; PFAM: alpha-acetolactate decarboxylase.
  
  
 0.564
Cwoe_1171
PFAM: Chorismate binding-like; aminotransferase class IV; KEGG: dol:Dole_1097 para-aminobenzoate synthase, subunit I.
  
 
 0.564
Cwoe_4927
Hypothetical protein.
       0.559
Your Current Organism:
Conexibacter woesei DSM 14684
NCBI taxonomy Id: 469383
Other names: C. woesei DSM 14684, Conexibacter woesei str. DSM 14684, Conexibacter woesei strain DSM 14684
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