STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cwoe_5792PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; AAA ATPase; KEGG: scl:sce3970 putative ATP-dependent helicase. (1480 aa)    
Predicted Functional Partners:
Cwoe_5804
DNA-(apurinic or apyrimidinic site) lyase; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: afw:Anae109_1725 DNA-(apurinic or apyrimidinic site) lyase; Belongs to the FPG family.
  
 0.953
Cwoe_5793
PFAM: Cupin 2 conserved barrel domain protein; KEGG: mca:MCA1001 hypothetical protein.
       0.718
Cwoe_5791
PFAM: Uracil-DNA glycosylase superfamily; KEGG: acp:A2cp1_3772 uracil-DNA glycosylase superfamily.
 
     0.678
Cwoe_5554
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: sme:SM_b20008 ATP-dependent DNA ligase.
 
    0.665
Cwoe_1111
PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; DNA glycosylase/AP lyase, H2TH DNA- binding; KEGG: ade:Adeh_3929 formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase.
 
  
 0.639
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
  
 0.636
Cwoe_3833
PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit.
  
     0.611
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.588
Cwoe_5824
PFAM: UvrD/REP helicase; KEGG: ank:AnaeK_0104 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
  
  
 0.553
Cwoe_5790
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: cti:RALTA_A1127 putative transcriptional egulator, TetR family.
       0.543
Your Current Organism:
Conexibacter woesei DSM 14684
NCBI taxonomy Id: 469383
Other names: C. woesei DSM 14684, Conexibacter woesei str. DSM 14684, Conexibacter woesei strain DSM 14684
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.