Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nanEHypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (224 aa)    
Predicted Functional Partners:
nanA
N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
 
  
 0.954
EEU33156.1
PTS system, N-acetylglucosamine-specific IIBC component.
    
 0.947
EEU32506.1
N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.943
EEU32315.1
PTS system, glucose subfamily, IIA component.
    
  0.909
EEU33091.1
Hypothetical protein.
  
 0.893
glmU
glmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
     
 0.831
EEU33090.1
TRAP transporter, DctM subunit.
     
 0.801
EEU32646.1
UTP-glucose-1-phosphate uridylyltransferase.
     
  0.800
EEU33087.1
Cyclically-permuted mutarotase.
 
  
 0.745
EEU33089.1
DctP family TRAP transporter solute receptor.
     
 0.624
Your Current Organism:
Fusobacterium nucleatum vincentii
NCBI taxonomy Id: 469604
Other names: F. nucleatum subsp. vincentii 3_1_36A2, Fusobacterium nucleatum subsp. vincentii 3_1_36A2, Fusobacterium sp. 3_1_36A2
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