node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFL82732.1 | EFL83526.1 | HMPREF0189_01227 | HMPREF0189_00604 | Homoserine dehydrogenase. | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.935 |
EFL82732.1 | asd | HMPREF0189_01227 | HMPREF0189_00751 | Homoserine dehydrogenase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.938 |
EFL82732.1 | dapA | HMPREF0189_01227 | HMPREF0189_02276 | Homoserine dehydrogenase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.772 |
EFL82732.1 | ilvN | HMPREF0189_01227 | HMPREF0189_01910 | Homoserine dehydrogenase. | Acetolactate synthase, small subunit. | 0.935 |
EFL83526.1 | EFL82732.1 | HMPREF0189_00604 | HMPREF0189_01227 | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | Homoserine dehydrogenase. | 0.935 |
EFL83526.1 | asd | HMPREF0189_00604 | HMPREF0189_00751 | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.967 |
EFL83526.1 | dapA | HMPREF0189_00604 | HMPREF0189_02276 | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.831 |
EFL83526.1 | dapF | HMPREF0189_00604 | HMPREF0189_01444 | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.780 |
asd | EFL82732.1 | HMPREF0189_00751 | HMPREF0189_01227 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase. | 0.938 |
asd | EFL83526.1 | HMPREF0189_00751 | HMPREF0189_00604 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.967 |
asd | dapA | HMPREF0189_00751 | HMPREF0189_02276 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.900 |
asd | dapF | HMPREF0189_00751 | HMPREF0189_01444 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.783 |
asd | ilvN | HMPREF0189_00751 | HMPREF0189_01910 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Acetolactate synthase, small subunit. | 0.775 |
asd | leuB | HMPREF0189_00751 | HMPREF0189_00750 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.875 |
asd | leuC | HMPREF0189_00751 | HMPREF0189_00748 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.739 |
asd | leuD | HMPREF0189_00751 | HMPREF0189_00749 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.729 |
asd | pgk | HMPREF0189_00751 | HMPREF0189_00343 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.844 |
asd | truA | HMPREF0189_00751 | HMPREF0189_00752 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.806 |
dapA | EFL82732.1 | HMPREF0189_02276 | HMPREF0189_01227 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Homoserine dehydrogenase. | 0.772 |
dapA | EFL83526.1 | HMPREF0189_02276 | HMPREF0189_00604 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.831 |