| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFL82102.1 | EFL82103.1 | HMPREF0189_02086 | HMPREF0189_02087 | Hypothetical protein. | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | 0.775 |
| EFL82102.1 | nusB | HMPREF0189_02086 | HMPREF0189_02090 | Hypothetical protein. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.776 |
| EFL82102.1 | pgpA | HMPREF0189_02086 | HMPREF0189_02088 | Hypothetical protein. | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.773 |
| EFL82102.1 | ribD | HMPREF0189_02086 | HMPREF0189_02093 | Hypothetical protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.509 |
| EFL82102.1 | ribH | HMPREF0189_02086 | HMPREF0189_02091 | Hypothetical protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.774 |
| EFL82102.1 | thiL | HMPREF0189_02086 | HMPREF0189_02089 | Hypothetical protein. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.778 |
| EFL82103.1 | EFL82102.1 | HMPREF0189_02087 | HMPREF0189_02086 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Hypothetical protein. | 0.775 |
| EFL82103.1 | nusB | HMPREF0189_02087 | HMPREF0189_02090 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.792 |
| EFL82103.1 | pgpA | HMPREF0189_02087 | HMPREF0189_02088 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.791 |
| EFL82103.1 | ribD | HMPREF0189_02087 | HMPREF0189_02093 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.594 |
| EFL82103.1 | ribH | HMPREF0189_02087 | HMPREF0189_02091 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.791 |
| EFL82103.1 | thiL | HMPREF0189_02087 | HMPREF0189_02089 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.791 |
| fmt | nusB | HMPREF0189_01497 | HMPREF0189_02090 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.847 |
| fmt | ribD | HMPREF0189_01497 | HMPREF0189_02093 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.418 |
| nusA | nusB | HMPREF0189_00621 | HMPREF0189_02090 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.915 |
| nusA | rpoZ | HMPREF0189_00621 | HMPREF0189_00506 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.916 |
| nusA | rpsJ | HMPREF0189_00621 | HMPREF0189_00093 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.979 |
| nusB | EFL82102.1 | HMPREF0189_02090 | HMPREF0189_02086 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Hypothetical protein. | 0.776 |
| nusB | EFL82103.1 | HMPREF0189_02090 | HMPREF0189_02087 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | 0.792 |
| nusB | fmt | HMPREF0189_02090 | HMPREF0189_01497 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.847 |