STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFS25676.1Hypothetical protein. (181 aa)    
Predicted Functional Partners:
dnaK
Chaperone dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.956
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.934
htpG
Chaperone htpG; Molecular chaperone. Has ATPase activity.
 
 0.932
EFS24487.1
Hypothetical protein.
  
 
 0.923
EFS26564.2
Hypothetical protein.
  
 0.910
EFS25945.1
Hydrogenase, Fe-only.
   
   0.864
EFS26315.1
Hypothetical protein.
 
 0.842
grpE
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
 
 
 0.825
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.797
EFS27613.1
1-acylglycerol-3-phosphate O-acyltransferase.
  
 
 0.797
Your Current Organism:
Fusobacterium ulcerans
NCBI taxonomy Id: 469617
Other names: F. ulcerans ATCC 49185, Fusobacterium ulcerans ATCC 49185
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.