Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrDDihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (305 aa)    
Predicted Functional Partners:
PyrK
Putative dihydroorotate dehydrogenase, electron transfer subunit.
 
 0.998
gltA
Glutamate synthase (NADPH), homotetrameric.
 0.998
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.994
EES62979.1
Amidohydrolase family protein.
 
 0.993
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.950
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.922
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 
 0.862
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 
  
 0.825
asrB
Sulfite reductase, subunit B.
 
 
 0.793
AsrB
Oxidoreductase NAD-binding domain protein.
 
 
 0.780
Your Current Organism:
Fusobacterium varium
NCBI taxonomy Id: 469618
Other names: F. varium ATCC 27725, Fusobacterium varium ATCC 27725
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