Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EES64594.1Putative toxin-antitoxin system, toxin component. (139 aa)    
Predicted Functional Partners:
EES64595.1
DNA-binding helix-turn-helix protein.
 
    0.895
EES63162.2
UvrD/REP helicase.
    
  0.594
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
  0.580
EES64596.1
Hypothetical protein.
       0.534
EES64593.1
Site-specific recombinase, phage integrase family; Belongs to the 'phage' integrase family.
       0.473
EES64855.1
DNA-binding helix-turn-helix protein.
 
  
 0.456
EES64597.1
Hypothetical protein.
       0.423
EES64598.1
Hypothetical protein.
       0.423
EES64599.1
Hypothetical protein.
       0.423
EES64600.1
Hypothetical protein.
       0.404
Your Current Organism:
Fusobacterium varium
NCBI taxonomy Id: 469618
Other names: F. varium ATCC 27725, Fusobacterium varium ATCC 27725
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