node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EES64652.1 | EES64653.1 | FVAG_01335 | FVAG_01336 | Peptidase, A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein. | 0.773 |
EES64652.1 | EES64658.1 | FVAG_01335 | FVAG_01341 | Peptidase, A24 family. | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | 0.879 |
EES64652.1 | ispF | FVAG_01335 | FVAG_01343 | Peptidase, A24 family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.611 |
EES64652.1 | rfaE-2 | FVAG_01335 | FVAG_01342 | Peptidase, A24 family. | Bifunctional protein RfaE, domain I. | 0.615 |
EES64653.1 | EES64652.1 | FVAG_01336 | FVAG_01335 | Prepilin-type cleavage/methylation N-terminal domain protein. | Peptidase, A24 family. | 0.773 |
EES64653.1 | EES64658.1 | FVAG_01336 | FVAG_01341 | Prepilin-type cleavage/methylation N-terminal domain protein. | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | 0.639 |
EES64653.1 | ispF | FVAG_01336 | FVAG_01343 | Prepilin-type cleavage/methylation N-terminal domain protein. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.589 |
EES64653.1 | rfaE-2 | FVAG_01336 | FVAG_01342 | Prepilin-type cleavage/methylation N-terminal domain protein. | Bifunctional protein RfaE, domain I. | 0.589 |
EES64658.1 | EES64652.1 | FVAG_01341 | FVAG_01335 | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | Peptidase, A24 family. | 0.879 |
EES64658.1 | EES64653.1 | FVAG_01341 | FVAG_01336 | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | Prepilin-type cleavage/methylation N-terminal domain protein. | 0.639 |
EES64658.1 | ispF | FVAG_01341 | FVAG_01343 | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.742 |
EES64658.1 | rfaE-2 | FVAG_01341 | FVAG_01342 | Bacterial type II and III secretion system protein; Belongs to the bacterial secretin family. | Bifunctional protein RfaE, domain I. | 0.722 |
dxr | dxs | FVAG_02814 | FVAG_00030 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.856 |
dxr | ispD | FVAG_02814 | FVAG_02870 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.855 |
dxr | ispE | FVAG_02814 | FVAG_02445 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.841 |
dxr | ispF | FVAG_02814 | FVAG_01343 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.856 |
dxr | ispG | FVAG_02814 | FVAG_00160 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.856 |
dxs | dxr | FVAG_00030 | FVAG_02814 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.856 |
dxs | ispD | FVAG_00030 | FVAG_02870 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.811 |
dxs | ispE | FVAG_00030 | FVAG_02445 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.753 |