Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EES64741.2ABC transporter, ATP-binding protein. (576 aa)    
Predicted Functional Partners:
EES64740.2
ABC transporter, ATP-binding protein.
 
  
 
0.984
EES62402.1
ABC transporter, substrate-binding protein, QAT family.
     
  0.728
EES64793.1
Hypothetical protein.
 
 0.579
EES64692.1
ABC transporter, ATP-binding protein.
 
     
0.578
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.557
EES65221.1
ABC transporter, ATP-binding protein.
   
0.552
cspE-2
Cold shock-like protein CspE.
   
 
 0.508
EES62764.1
ABC transporter, ATP-binding protein.
 
 0.487
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
 0.478
EES63415.1
DnaJ domain protein.
  
 
 0.439
Your Current Organism:
Fusobacterium varium
NCBI taxonomy Id: 469618
Other names: F. varium ATCC 27725, Fusobacterium varium ATCC 27725
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